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Natural Hormone Creams
Compounding Pharmacies provide natural hormone creams by prescription. If your doctor does not know what to order they can call the pharmacists at the pharmacies mentioned below for details on what to prescribe. Your hormones will be mailed directly to you.
What are natural hormones?
Bioidentical hormones: tri-est, natural progesterone, natural testosterone
| Estradiol - E2 |
Progesterone |
Thyroid |
| Estriol - E3 |
Testosterone |
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Estrone - E1
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Biest - E3/E2
(80%/20%) |
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Triest - E3/E2/E1
(80%/10%/10%) |
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ESTRADIOL (E2)
Estradiol, the principal estrogen found in a woman's body during the reproductive years, is produced by the ovaries. Estradiol is very effective for the symptomatic relief of hot flashes, genitourinary symptoms, osteoporosis prophylaxis, psychological well-being and reduction of coronary artery disease.
Because it is much more potent than estriol, it can be more effective for symptomatic relief than estriol. When Estradiol is replaced using a parenteral (sublingual, percutaneous, or transdermal) route, it is not subject to first pass metabolism by the liver, and therefore does no produce high levels of estrone. Using these routes of administration a woman can mimic the physiologic release of estradiol from the ovaries, thus receiving natural hormone replacement.
ESTRIOL (E3)
Estriol is the weakest of the three major estrogens. In fact it is 1000 times weaker in its effect on breast tissue. Estriol is the estrogen that is made in large quantities during pregnancy and has potential protective properties against the production of cancerous cells.
An important article in the 1966 Journal of the American Medical Association by H.M. Lemmon, M.D., reported a study showing that higher levels of estriol in the body correlate with remission of breast cancer. Dr. Lemmon demonstrated that women with breast cancer had reduced urinary excretion of estriol. He also observed that women without breast cancer have naturally higher estriol levels, compared with estrone and estradiol levels, than women with breast cancer. Vegetarian and Asian women have high levels of estriol, and these women are at much lower risk of breast cancer than are other women. Estriol's anti-cancer effect is probably related to its anti-estrone properties-it blocks the stimulatory effect of estrone by occupying the estrogen receptor sites on the breast cells.
Estriol is the estrogen most beneficial to the vagina, cervix and vulva. In cases of vaginal dryness and atrophy, which predisposes a woman to vaginitis and cystitis, topical estriol is the most effective and safest estrogen to use. Because of this estriol is better than estradiol for the treatment of urinary tract infections.
None of the American drug products contain Estriol, so it is not available in most drug stores, although it has been used widely in Europe for over fifty years. Because estriol cannot be patented it does not hold much interest for the pharmaceutical industry. Its availability through compounding has caused its use to grow rapidly throughout the country.
ESTRONE (E1)
Estrone is the estrogen most commonly found in increased amounts in postmenopausal women. The body derives it from the hormones that are stored in body fat. Estrone does the same work that estradiol does, but it is considered weaker in its effects.
BI-ESTROGEN(BIEST)
Bi-estrogen, as the word might indicate, is a combination of two estrogens; Estriol (E-3), and Estradiol (E-2). These two estrogens are 2 of the 3 natural occurring or (bio-identical) estrogens found in the female body.
BI-ESTROGEN = ESTRIOL + ESTRADIOL
ESTRIOL is one of the three active estrogen found in the female body. Estriol is the dominant estrogen during pregnancy. Estriol is a converted estrogen. It is the end metabolite of both estradiol and estrone metabolism. Estriol is considered by many to be the "forgotten" estrogen. It has been labeled in the US as a weak or ineffective estrogen, while in Europe, estriol has been recognized for its benefits and has been used for years. Estriol has a much less stimulating effect on the breast tissue and the uterine lining than both estradiol and estrone. Estradiol is 1000 times more stimulating to the breast tissue than estriol. Since estriol is the weakest of the three naturally occurring estrogens in estrogen activity, but comprises nearly 80% of the total free estrogen in the female body, estriol is thought to have a protective effect in the female body. That is, when estriol levels become low there is less of this weak estrogen to occupy estrogen receptor sites, therefore leaving more estrogen sites available to be stimulated by the stronger estrogens estradiol and estrone. Some researchers believe that not only does estriol no promote breast cancer, but actually protects against the disease. In 1966, H.M. Lemon, MD demonstrated that women with breast cancer have lower estriol levels. He later showed that women without breast cancer had naturally higher estriol levels than those with breast cancer. Estriol is the weakest of the three estrogen when used topically and orally but considered the strongest when used locally to the vaginal canal. And therefore is thought to be a preferred estrogen when used vaginally. When using low does of estriol, no significant uterine or breast stimulation is usually observed. Estriol is therefore sometimes used in the high-risk patient where estrogen therapy needs to be extremely conservative.
ESTRADIOL is the strongest of the three naturally occurring estrogens found in the female body. It is the most important and significant estrogen throughout a woman's productive life. Estradiol is the most active of the three estrogens. It is primarily produced by the ovaries. When we speak of the benefits of estrogen most generally, we think of estradiol as the main participant. It is the most potent and also the most beneficial estrogen in controlling all the estrogen deficient symptoms associated with menopause. Estradiol is also recognized to be the most significant estrogen in raising high-density lipoproteins (HDL) the good cholesterol, maintaining bone mass, possible protection from Alzheimer's disease, improved skin, and many more. Because of its relative activity compared to the other estrogens, estradiol can also be blamed for many estrogen dominant characteristics such as uterine proliferation, breast stimulation and tenderness, breast cancer, fluid retention, increased body fat, reduced thyroid function to mention a few. But most if not all of these undesirable estrogen dominant characteristics can be overcome with the proper balance of the natural estrogens and the use of Natural Progesterone along with the estrogen therapy.
WHY USE A BI-ESTROGEN?
The key to the success of any hormone replacement therapy (HRT) program is the balancing of the body's natural hormone levels so that they will mimic the normal psysiologic hormonal levels for that specific person. Many times, different natural hormone (NH) compounds are prescribed as a matter of practitioner preference or personal good luck or experience with a preparation. Certainly not to be overlooked is patient preference. Through patient education, people have developed their own ideas on how they wish their HRT program to be structured. When a woman enters menopause, Estrone (E-1) the third estrogen, becomes dominant as the ovaries stop producing estradiol. Estrone at this time is produced by the adrenals and in the fat tissue of the body. Because estrone can be produced in the fat tissue of the body, depending on an individual (over weight) and diet, estrone levels can remain high. It would then make sense of we have an abundance of estrone at menopause we might choose to supplement with only Estriol and Estradiol (thus Bi-estrogen) to maintain proper balance of the body's natural hormones. Remember, the balance of these hormones to each other is the key to a successful HRT program.
SOURCE OF NATURAL (BIO-IDENTICAL) ESTROGENS
We compound all of our hormonal preparations using only all natural (bio-identical), soy (plant derived), USP grade, micronized, hormone powders. When we say bio-identical, we mean exactly like the human body produces. We use no animal products. These products must not be confused with phyto (plant) products which may mimic to a small degree some of the body's own hormones, but are not considered to be bio-identical hormones. All of our compounded preparations require a prescription from a licensed practitioner.
SOME OF THE EFFECTS OF TOO MUCH ESTROGEN IN WOMEN
- Uterine bleeding
- Tender swollen breasts
- Water retention
- Increased body fat
- Headaches
- Hypertension
- Irritability
COMPOUNDED PREPARATIONS AVAILABLE
Oral capsules: Using natural gelatin capsules with hormone suspended in a cold pressed natural safflower oil with vitamin E added. Oil filled oral capsules known to give the best absorption f oral hormones. For best absorption should be taken with food. Usually give more consistent results when dosed twice a day.
Topical Gels: Using a base known as a hydro-alcoholic gel. USP alcohol is added for stability and efficacy. No oils, no petroleum additives, no perfumes. This type of base has been used in Europe for years. As an industry standard known to be the best for delivery of topically applied hormones. Strength of gels designated as mg's per 1/4 teaspoonful. Should be applied to inner arms, inner thighs or tummy. No neck, no face, no mucous membranes. Use at least three consecutive days to one area for better tissue saturation and better results. Should be dosed twice a day if possible, to give more consistent results (Little dose spoons we give with topical preparations measure 1/8 teaspoonful when leveled off).
Vaginals: Either gel base or vanishing cream base. Can use applicator or finger dab. Generally do not need a high introduction in vaginal canal and therefore finger dab may be more convenient.
Combinations: Progesterone, Testosterone, DHEA may be added to any formula upon order from practitioner. (Exception… we do not usually add these hormones to the vaginal preparations).
MOST COMMON STRENGTHS
1.25mg and 2.5 mg (2.5mg orally given twice a day approximately = to .625mg conjugated estrogen)
***Doses should always be individualized. ***We have over 900 formulas to choose from.
STRENGTH TRANSLATION
There is NO general rule for a Bi-estrogen: Bi-estrogen = estriol + estradiol
Example:
Bi-est 2.5mg = 2mg estriol + .5mg estradiol
Bi-est 2/1mg = 2mg estriol + 1mg estradiol
The first number in the strength designation is always ESTRIOL and the second number after the decimal (.) or back-slash (/) is always ESTRADIOL.
TRIEST
Triest is a combination of three estrogens: estriol, estradiol and estrone. It is most commonly found in a ratio of 80:10:10, estriol, estradiol, and estrone. This combination is very popular and contains all of the three major circulating estrogens. It is slightly weaker in its effect when compared to biest. However, this can be compensated for by increasing the strength or by slightly changing the ratios.
PROGESTERONE
Progesterone is produced by the ovaries and the adrenal glands in women and, in smaller amounts, in the testes and the adrenal glands in men. One of its most important functions is in the female reproductive cycle. Progesterone prepares the lining of the uterus for implantation of a fertilized egg, then helps to maintain it during pregnancy. If pregnancy does not occur it signals the uterus to shed this lining.Progesterone also plays an important role in brain function and is often called the "feel good hormone" because of its mood enhancing and anti-depressant effects. Optimum levels of progesterone can mean feelings of calm and well being, while low levels of progesterone can mean feelings of anxiety, irritability and even anger. Current research shows that progesterone may play a role in the maintenance of the nervous system, the sense of touch, and motor function.
Progesterone Cream List - from Aeron Life-Cycles website click below for more information
Product Integrity Certification Program
Aeron LifeCycles Clinical Laboratory sponsors the Product Integrity Certification (PIC) program which tests and certifies over-the-counter progesterone cream products. For a fee, manufacturers and distributors subscribe to the PIC program in which their cream, by lot number, is tested for its progesterone concentration by an outside reference laboratory. The PIC list is published quarterly listing each cream by its product name, manufacturer, amount of progesterone per ounce cream and lot number.
With the many new progesterone-containing cream products becoming available in the marketplace, the PIC list provides valuable information when the consumer is making choices.
Aeron certifies that the cream products listed below contain the stated amount of progesterone. Aeron assumes no responsibility for the performance of the products tested. This listing is produced as a service to consumers interested in knowing the progesterone content in topical creams and lotions. Aeron does not manufacture, sponsor or advocate the use of any particular product.
Progesterone Content of Body Cream
Product Integrity Certification Program "PIC"
December 15, 1999
| Brand Name | Manufacturer | Progesterone
mg/oz cream | Lot # | Phone # |
| Angel Care | Angel Care USA | 648 mg | 9667 | (800) 854-3895 |
| Angel Care | Angel Care USA | 648 mg | 9668 | (800) 854-3895 |
| Angel Care | Angel Care USA | 579 mg | 9669 | (800) 854-3895 |
| Balance Cream | Vitality Lifechoice | 517 mg | 498 | (775) 882-6611 |
| Balance Cream | Vitality Lifechoice | 447 mg | 9074E | (775) 882-6611 |
| Balance Cream | Vitality Lifechoice | 470 mg | 110-75 | (775) 882-6611 |
| DermaGest | Broadmoore Labs | 510 mg | 4.77E+29 | (800) 822-3712 |
| EssPro 7 | Young Living Essential | 548 mg | 70899 | (800) 763-9963 |
| Femarone 17 | Wise Essentials | 536 mg | 8126 | (800) 295-2256 |
| Femarone | Wise Essentials | 0 mg | 6255 | (800) 295-2256 |
| Fem-Gest | Bio-Nutritional Formulas | 431 mg | 12916 | (800) 950-8484 |
| Renascence Progesterone | Marpe' International | 1586 mg | 2P123 | (800) 295-3477 |
| Maxine's Feminique | Country Life | 443 mg | 811053 | (800) 645-5768 |
| NatraGest | Broadmoore Labs | 446 mg | 2699 | (800) 822-3712 |
| Procreme | THG Health Products | 489 mg | 17-125 | (800) 677-7694 |
| Procreme Plus | THG Health Products | 926 mg | 812-A | (800) 677-7694 |
| Progesterone Cream Max | Jason Natural Cosmetics | 480 mg | 9152-B | (310) 838-7543 |
| Progesterone Cream Light | Jason Natural Cosmetics | 240 mg | 9152-C | (310) 838-7543 |
| ProL'eve | Brain Garden | 542 mg | 103AS | (800) 481-9987 |
| SupraGest | Health Alternatives West | 452 mg | 13704 | (877) 984-9286 |
| Ultra Harmony | Wise Woman Essentials | 0 mg | 7035 | (800) 295-2256 |
| Wild Yam Crème W/Prog | Wise Woman Essentials | 525 mg | 8125 | (800) 295-2256 |
TESTOSTERONE
Usually considered a male hormone or androgen, women also produce testosterone although in much smaller amounts than men do. Testosterone works differently in the bodies of men and women, but it plays a very important role in the overall health and well being of both sexes. Often called the "hormone of desire" because of its powerful effect on libido, testosterone is also important in building strong muscles, bones, and ligaments as well as increasing energy and easing depression. Low levels of testosterone have been known to cause fatigue, irritability, depression, aches and pain in the joints, thin and dry skin, osteoporosis, weight loss, and the loss of muscle development. As with all of the hormones, testosterone must be dosed properly to be effective without causing unwanted side effects. The dose in women is generally one-tenth that used in men. Because testosterone is not effective when it is taken orally it is usually prescribed as a topical gel, cream or as a sublingual tablet. Although testosterone was discovered more than sixty years ago, only very recently have we begun to fully understand and appreciate the power of testosterone
Where to buy Natural Hormone Creams
York Downs Pharmacy ships all over North America
York Downs Pharmacy
3910 Bathurst Street
North York, Ontario
M3H 3N8
North American Toll Free 1-800-564-5020
Toronto area 416 633-2244
E-mail san.pharmacy@sympatico.ca
College Pharmacy Compounding Specialists
North American Toll free: 1 - 800 - 888 - 9358 or
Colorado Springs: 719 - 262 - 0022
Fax: 1 - 800 - 556 - 5893 or 719 - 262 - 0035
3505 Austin Bluffs Parkway
Colorado Springs, CO 80907
E-mail: info@collegepharmacy.com
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